Milrinone and levosimendan administered after reperfusion improve myocardial stunning in swine
نویسندگان
چکیده
منابع مشابه
Milrinone and levosimendan administered after reperfusion improve myocardial stunning in swine.
OBJECTIVES We assessed the effect of milrinone application timing after reperfusion against myocardial stunning as compared with levosimendan in swine. Furthermore, we examined the role of p38 mitogen-activated protein kinase (p38 MAPK) in the milrinone-induced cardioprotection. DESIGN All swine were subjected to 12-minutes ischemia followed by 90-minutes reperfusion to generate stunned myoca...
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The pathophysiologic mechanisms underlying myocardial stunning, especially following heart surgery, are fascinating and optimal treatment of the condition is of fundamental importance. We therefore read the recent article by Álvarez et al1 with great interest and we must congratulate the authors on their excellent work. Nevertheless, we would like to make the following observations. At least 14...
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ژورنال
عنوان ژورنال: Scandinavian Cardiovascular Journal
سال: 2012
ISSN: 1401-7431,1651-2006
DOI: 10.3109/14017431.2012.732236